Decline in the average rate of linear growth and increased mineralization of bones in infants and children (dwarfism).Bone demineralization (osteoporosis) in adults occurs concomitantly. Widespread calcification of the soft tissues, including the heart, blood vessels, renal tubules, and lungs.
Impairment of renal function with polyuria, nocturia, polydipsia, hypercalciuria, reversible azotemia, hypertension, nephrocalcinosis, generalized vascular calcification, or irreversible renal insufficiency which may result in death.Hypercalcemia with anorexia, nausea, weakness, weight loss, vague aches and stiffness, constipation, mental retardation, anemia, and mild acidosis.The effects of administered vitamin D can persist for two or more months after cessation of treatment.
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